PLAAT1

Across TCGA cell cohorts, PLAAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,838 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLAAT1-associated GO terms across cancer lineages are Nucleotide biosynthetic process, Positive regulation of monoatomic ion transport, and Regulation of heart rate. Each is linked with PLAAT1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PLAAT1-to-partner and partner-to-PLAAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide biosynthetic process grouped by PLAAT1-low versus PLAAT1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAAT1→partner) and Y-score (partner→PLAAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nucleotide biosynthetic process →	+0.065	+1.840	.006	.001	3	10
STOMACH	Positive regulation of monoatomic ion transport →	-0.080	-1.101	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of heart rate →	-0.107	-1.010	.005	.009	3	10
BONE	Nucleoside phosphate biosynthetic process →	+0.062	+1.722	.004	<.001	2	11
OVARY	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.087	-1.828	<.001	<.001	3	9
STOMACH	Gamma-aminobutyric acid signaling pathway →	-0.371	-1.721	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,838 associations by consensus.

Nucleotide biosynthetic process by PLAAT1 expression — LUNG_SCLC

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