PLA2G7

Across TCGA patient cohorts, PLA2G7 protein abundance is significantly associated with the RNA expression of many other genes, with 6,031 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLA2G7-associated genes across cancer lineages are AQP9, CSF3R, and CCRL2. Each is linked with PLA2G7 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLA2G7-to-partner and partner-to-PLA2G7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G7 versus AQP9 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G7→partner) and Y-score (partner→PLA2G7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AQP9 →	+1.202	+0.410	.002	.001	3	5
LSCC	CSF3R →	+1.044	+0.534	<.001	<.001	3	5
GBM	CCRL2 →	+1.084	+0.686	<.001	<.001	3	5
GBM	BCL2A1 →	+1.363	+0.463	<.001	.001	3	5
GBM	HK3 →	+1.047	+0.444	<.001	.003	3	5
GBM	CTSS →	+1.124	+0.502	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,031 associations by consensus.

PLA2G7 vs AQP9 — GBM

Explore this scatter interactively →