PLA2G4F

Across TCGA cell cohorts, PLA2G4F mutation is significantly associated with the RNA expression of many other genes, with 324 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLA2G4F-associated genes across cancer lineages are APCS, FAXC, and NPBWR2. Each is linked with PLA2G4F in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G4F-to-partner and partner-to-PLA2G4F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APCS grouped by PLA2G4F-low versus PLA2G4F-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4F→partner) and Y-score (partner→PLA2G4F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	APCS →	+0.060	+3.786	<.001	.002	3	2
LARGE_INTESTINE	FAXC →	+1.396	+2.502	<.001	.005	3	2
PANCREAS	NPBWR2 →	+0.023	+5.000	<.001	.006	3	1
PANCREAS	HMGB4 →	+0.015	+5.000	.008	.006	3	1
PANCREAS	KRTAP20-2 →	+0.126	+5.614	<.001	.002	3	1
BLOOD_Leukemia	MUCL3 →	+0.054	+3.177	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 324 associations by consensus.

APCS by PLA2G4F expression — BLOOD_Leukemia

Explore this box plot interactively →