PLA2G4B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLA2G4B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,738 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLA2G4B-associated GO terms across cancer lineages are mRNA splice site recognition, Taurine biosynthetic process, and Alkanesulfonate biosynthetic process. Each is linked with PLA2G4B in more than 14 cancer types. Because this analysis shows association rather than direction, both PLA2G4B-to-partner and partner-to-PLA2G4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by PLA2G4B-low versus PLA2G4B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4B→partner) and Y-score (partner→PLA2G4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEmRNA splice site recognition →+0.111+0.887<.001<.001315
BONETaurine biosynthetic process →+1.046+0.827.007.003314
BONEAlkanesulfonate biosynthetic process →+1.046+0.827.007.003314
LUNG_NSCLC_LUADCilium movement involved in cell motility →-0.076-0.828<.001<.001314
BONECo-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →+0.112+0.716<.001<.001313
BONELate viral transcription →+0.136+0.866.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,738 associations by consensus.

mRNA splice site recognition by PLA2G4B expression — SOFT_TISSUE

Box plot of mRNA splice site recognition in PLA2G4B-low vs PLA2G4B-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration