PLA2G2F

Across TCGA patient cohorts, PLA2G2F mutation is significantly associated with the RNA expression of many other genes, with 685 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLA2G2F-associated genes across cancer lineages are RNA5SP321, MIR4510, and H3P2. Each is linked with PLA2G2F in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G2F-to-partner and partner-to-PLA2G2F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP321 grouped by PLA2G2F-low versus PLA2G2F-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G2F→partner) and Y-score (partner→PLA2G2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP321 →	+0.284	+4.539	<.001	.008	3	2
CESC	MIR4510 →	+0.287	+5.342	<.001	.002	3	2
SKCM	H3P2 →	+0.075	+2.968	.001	.005	3	2
SKCM	RN7SL757P →	+0.051	+3.990	<.001	.009	3	2
UCEC	HSPE1-MOB4 →	+0.159	+3.078	.003	<.001	3	2
UCEC	SNRPGP17 →	+0.233	+2.463	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 685 associations by consensus.

RNA5SP321 by PLA2G2F expression — CESC

Explore this box plot interactively →