PLA2G2F

Across TCGA cell cohorts, PLA2G2F mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PLA2G2F-associated genes across cancer lineages are SPINK9 and CCL13. Each is linked with PLA2G2F in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G2F-to-partner and partner-to-PLA2G2F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPINK9 grouped by PLA2G2F-low versus PLA2G2F-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G2F→partner) and Y-score (partner→PLA2G2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SPINK9 →	+0.043	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	CCL13 →	+0.025	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPINK9 by PLA2G2F expression — SKIN

Explore this box plot interactively →