Across TCGA pan-cancer cohorts, PLA2G2E Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PLA2G2E data layer compared with 17 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PLA2G2E Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PLA2G2E expression acts as an unfavorable survival marker.

UCEC are the cancer types where PLA2G2E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: PLA2G2E tumor-vs-normal RNA expression · all PLA2G2E data types