PLA2G1B

Across TCGA cell cohorts, PLA2G1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,544 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLA2G1B-associated GO terms across cancer lineages are Skeletal myofibril assembly, Phosphatidylserine catabolic process, and Regulation of CD4-positive, alpha-beta T cell differentiation. Each is linked with PLA2G1B in more than 3 cancer types. Because this analysis shows association rather than direction, both PLA2G1B-to-partner and partner-to-PLA2G1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal myofibril assembly grouped by PLA2G1B-low versus PLA2G1B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G1B→partner) and Y-score (partner→PLA2G1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Skeletal myofibril assembly →	-0.509	-0.212	<.001	<.001	3	4
SOFT_TISSUE	Phosphatidylserine catabolic process →	+0.103	+0.176	<.001	.002	3	4
CNS	Regulation of CD4-positive, alpha-beta T cell differentiation →	-0.057	-0.094	<.001	.002	3	4
CNS	Regulation of T-helper cell differentiation →	-0.070	-0.100	.001	.001	3	4
CNS	Proton-transporting two-sector ATPase complex assembly →	+0.049	+0.120	.007	.006	3	4
SOFT_TISSUE	Positive regulation of B cell mediated immunity →	-0.075	-0.126	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,544 associations by consensus.

Skeletal myofibril assembly by PLA2G1B expression — BLOOD_Leukemia

Explore this box plot interactively →