PLA2G15

Across TCGA patient cohorts, PLA2G15 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,075 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLA2G15-associated proteins across cancer lineages are PLBD2, PLD3, and CTSZ. Each is linked with PLA2G15 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLA2G15-to-partner and partner-to-PLA2G15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G15 versus PLBD2 in GBM, with a Pearson correlation of 0.70.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G15→partner) and Y-score (partner→PLA2G15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLBD2 →	+0.465	+0.442	<.001	<.001	3	9
LSCC	PLD3 →	+0.496	+0.460	<.001	<.001	3	8
GBM	CTSZ →	+0.567	+0.301	<.001	<.001	3	8
LUAD	NAGK →	+0.291	+0.310	<.001	<.001	3	8
PDAC	NECAP2 →	+0.354	+0.298	.001	<.001	3	7
GBM	NPC2 →	+0.738	+0.388	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,075 associations by consensus.

PLA2G15 vs PLBD2 — GBM

Explore this scatter interactively →