PLA2G15

Across TCGA cell cohorts, PLA2G15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,605 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLA2G15-associated GO terms across cancer lineages are Protein targeting, Caveolin-mediated endocytosis, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with PLA2G15 in more than 13 cancer types. Because this analysis shows association rather than direction, both PLA2G15-to-partner and partner-to-PLA2G15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting grouped by PLA2G15-low versus PLA2G15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G15→partner) and Y-score (partner→PLA2G15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein targeting →	+0.071	+1.861	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Caveolin-mediated endocytosis →	+0.206	+1.026	<.001	.002	3	14
SOFT_TISSUE	Multi-pass transmembrane protein insertion into ER membrane →	+0.144	+1.037	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.063	+0.988	.001	.002	3	13
BONE	Proteoglycan catabolic process →	+0.167	+1.404	<.001	<.001	3	13
BONE	Collagen biosynthetic process →	+0.297	+1.356	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,605 associations by consensus.

Protein targeting by PLA2G15 expression — BONE

Explore this box plot interactively →