PLA2G12A

Across TCGA pan-cancer cohorts, PLA2G12A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PLA2G12A data layer compared with 22 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher PLA2G12A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PLA2G12A expression acts as an unfavorable survival marker.

OV are the cancer types where PLA2G12A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.132	0.541	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

PLA2G12A–OV (DFS)

Open the OV breakdown →