PLA2G12A

Across TCGA patient cohorts, PLA2G12A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,084 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLA2G12A-associated proteins across cancer lineages are CASP6, LRBA, and MLKL. Each is linked with PLA2G12A in more than 5 cancer types. Because this analysis shows association rather than direction, both PLA2G12A-to-partner and partner-to-PLA2G12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G12A versus CASP6 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G12A→partner) and Y-score (partner→PLA2G12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CASP6 →	+0.470	+0.668	<.001	<.001	3	6
BRCA	LRBA →	+0.524	+0.851	<.001	<.001	3	5
BRCA	MLKL →	-0.434	-0.643	<.001	<.001	3	5
BRCA	DDAH1 →	+0.787	+0.781	<.001	<.001	3	5
GBM	TNFAIP8 →	-0.782	-0.325	<.001	.004	3	5
BRCA	CRLF3 →	-0.408	-0.630	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,084 associations by consensus.

PLA2G12A vs CASP6 — OV

Explore this scatter interactively →