PLA2G12A

Across TCGA patient cohorts, PLA2G12A protein abundance is significantly associated with the protein abundance of many other proteins, with 4,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLA2G12A-associated proteins across cancer lineages are BRD4_S1045, RGS14_S203, and SEC24A_T225. Each is linked with PLA2G12A in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G12A-to-partner and partner-to-PLA2G12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G12A versus BRD4_S1045 in BRCA, with a Pearson correlation of -0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G12A→partner) and Y-score (partner→PLA2G12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BRD4_S1045 →	-0.919	-0.835	.001	.001	3	2
BRCA	RGS14_S203 →	-1.317	-1.112	<.001	.001	3	1
BRCA	SEC24A_T225 →	+1.117	+0.907	.002	.002	3	1
BRCA	SEPTIN9_S30 →	+0.638	+1.071	<.001	.004	3	1
BRCA	SH3KBP1_S509 →	-0.893	-0.871	.001	<.001	3	1
BRCA	SMAD1 →	+1.043	+1.140	.002	.003	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,359 associations by consensus.

PLA2G12A vs BRD4_S1045 — BRCA

Explore this scatter interactively →