PLA2G12A

Across TCGA cell cohorts, PLA2G12A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLA2G12A-associated genes across cancer lineages are CRISP1. Each is linked with PLA2G12A in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G12A-to-partner and partner-to-PLA2G12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRISP1 grouped by PLA2G12A-low versus PLA2G12A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G12A→partner) and Y-score (partner→PLA2G12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CRISP1 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CRISP1 by PLA2G12A expression — LARGE_INTESTINE

Explore this box plot interactively →