PLA1A

Across TCGA cell cohorts, PLA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,332 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PLA1A-associated GO terms across cancer lineages are ER-nucleus signaling pathway, Vacuole organization, and Regulation of kidney size. Each is linked with PLA1A in more than 6 cancer types. Because this analysis shows association rather than direction, both PLA1A-to-partner and partner-to-PLA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ER-nucleus signaling pathway grouped by PLA1A-low versus PLA1A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA1A→partner) and Y-score (partner→PLA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ER-nucleus signaling pathway →	+0.076	+1.832	.006	.007	3	7
KIDNEY	Vacuole organization →	+0.047	+2.276	.002	<.001	3	6
OVARY	Regulation of kidney size →	+1.298	+0.584	<.001	.002	3	6
BLOOD_Lymphoma	Lung morphogenesis →	+0.382	+0.647	.006	.006	3	5
LARGE_INTESTINE	Positive regulation of cytosolic calcium ion concentration →	-0.058	-0.464	<.001	<.001	3	5
BLOOD_Lymphoma	Lymphocyte apoptotic process →	+0.091	+1.140	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,332 associations by consensus.

ER-nucleus signaling pathway by PLA1A expression — LIVER

Explore this box plot interactively →