Across TCGA patient cohorts, PKP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,651 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PKP3-associated proteins across cancer lineages are PKP3_S130, PKP3_S180, and EPS8L2. Each is linked with PKP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PKP3-to-partner and partner-to-PKP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKP3→partner) and Y-score (partner→PKP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PKP3_S130 →	+2.627	+3.862	<.001	<.001	3	6
CCRCC	PKP3_S180 →	+2.783	+2.992	<.001	<.001	3	6
HNSC	EPS8L2 →	+0.619	+0.994	<.001	<.001	3	6
HNSC	STIM1 →	+0.392	+1.652	<.001	<.001	3	5
LSCC	BAIAP2L1 →	+0.513	+0.775	<.001	<.001	3	5
BRCA	LARP4_S583 →	+0.414	+0.743	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,651 associations by consensus.

Exploration

PKP3 survival (RNA) · tumor vs normal (RNA) · all PKP3 data types