Across TCGA cell cohorts, PKP3 RNA expression is significantly associated with the RNA expression of many other genes, with 9,736 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PKP3-associated genes across cancer lineages are C6orf132, EPS8L2, and CEP170B. Each is linked with PKP3 in more than 13 cancer types. Because this analysis shows association rather than direction, both PKP3-to-partner and partner-to-PKP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKP3→partner) and Y-score (partner→PKP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	C6orf132 →	+3.411	+3.062	<.001	<.001	3	14
LUNG_SCLC	EPS8L2 →	+3.018	+3.724	<.001	<.001	3	14
SOFT_TISSUE	CEP170B →	+1.662	+1.439	<.001	<.001	2	14
URINARY_TRACT	GJB3 →	+3.208	+2.243	<.001	<.001	3	13
STOMACH	ATP2C2 →	+2.392	+2.444	<.001	<.001	3	13
OVARY	TMEM184A →	+2.420	+3.217	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,736 associations by consensus.

Exploration

PKP3 survival (RNA) · tumor vs normal (RNA) · all PKP3 data types