PKNOX2

Across TCGA patient cohorts, PKNOX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,623 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PKNOX2-associated proteins across cancer lineages are FERMT2, OLFML3, and KANK2. Each is linked with PKNOX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PKNOX2-to-partner and partner-to-PKNOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKNOX2 versus FERMT2 in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKNOX2→partner) and Y-score (partner→PKNOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FERMT2 →	+0.611	+0.177	<.001	.001	3	8
UCEC	OLFML3 →	+0.909	+0.920	<.001	<.001	3	8
UCEC	KANK2 →	+0.693	+0.605	<.001	.003	3	7
UCEC	HDGFL3 →	+0.663	+0.698	<.001	.002	3	7
HNSC	NID1 →	+0.684	+0.735	<.001	<.001	3	7
UCEC	TNS1 →	+0.718	+0.730	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,623 associations by consensus.

PKNOX2 vs FERMT2 — COAD

Explore this scatter interactively →