PKN2

Across TCGA patient cohorts, PKN2 RNA expression is significantly associated with the RNA expression of many other genes, with 21,381 significant associations in total. THYM shows the largest number of these associations.

The most reproducible PKN2-associated genes across cancer lineages are MAPK1, DDX17, and TCF20. Each is linked with PKN2 in more than 33 cancer types. Because this analysis shows association rather than direction, both PKN2-to-partner and partner-to-PKN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKN2 versus MAPK1 in THYM, with a Pearson correlation of 0.92.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKN2→partner) and Y-score (partner→PKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	MAPK1 →	+1.262	+1.258	<.001	<.001	3	34
UVM	DDX17 →	+1.431	+1.908	<.001	<.001	3	34
DLBC	TCF20 →	+0.981	+1.056	<.001	<.001	3	34
DLBC	HMGXB4 →	+1.258	+1.154	<.001	<.001	3	34
SCLC	TNRC6B →	+1.294	+0.763	<.001	<.001	3	34
DLBC	EP300 →	+1.984	+1.259	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,381 associations by consensus.

PKN2 vs MAPK1 — THYM

Explore this scatter interactively →