PKN2

Across TCGA patient cohorts, PKN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,963 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PKN2-associated proteins across cancer lineages are PAF1, ZNF326, and CDC73. Each is linked with PKN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PKN2-to-partner and partner-to-PKN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKN2 versus PAF1 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKN2→partner) and Y-score (partner→PKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAF1 →	+0.292	+0.486	<.001	<.001	3	6
LSCC	ZNF326 →	+0.373	+0.506	<.001	<.001	3	5
LSCC	CDC73 →	+0.273	+0.499	.001	.001	3	5
LSCC	SAE1 →	+0.227	+0.518	.002	<.001	3	5
HNSC	SAR1B →	-0.352	-0.447	<.001	<.001	3	5
PDAC	LRRC41 →	+0.330	+0.374	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,963 associations by consensus.

PKN2 vs PAF1 — LSCC

Explore this scatter interactively →