Across TCGA pan-cancer cohorts, PKMP5 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PKMP5 data layer.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PKMP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PKMP5 expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.
LUAD, MESO, and KIRC are the cancer types where PKMP5 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.