PKDCC

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PKDCC Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PKDCC data layer compared with 24 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PKDCC Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PKDCC expression acts as an unfavorable survival marker.

STAD are the cancer types where PKDCC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianAll0.0980.539.00812view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

PKDCC–STAD (OS)

Kaplan–Meier survival curve for PKDCC mutant vs wild-type samples in STAD.

Open the STAD breakdown →

Exploration