PKD2

Across TCGA patient cohorts, PKD2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,695 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PKD2-associated genes across cancer lineages are CHPF, MXRA8, and FGF1. Each is linked with PKD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PKD2-to-partner and partner-to-PKD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKD2 versus CHPF in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD2→partner) and Y-score (partner→PKD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CHPF →	+0.588	+0.365	.001	.001	3	5
OV	MXRA8 →	+1.619	+0.565	<.001	<.001	3	5
OV	FGF1 →	+1.118	+0.450	<.001	<.001	3	4
OV	C1QTNF3 →	+1.147	+0.448	<.001	<.001	3	4
OV	GEM →	+1.050	+0.495	.006	<.001	3	4
OV	ANTXR1 →	+0.877	+0.432	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,695 associations by consensus.

PKD2 vs CHPF — OV

Explore this scatter interactively →