PKD2

Across TCGA cell cohorts, PKD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,185 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PKD2-associated GO terms across cancer lineages are Cellular response to hydrostatic pressure, Golgi vesicle transport, and Response to hydrostatic pressure. Each is linked with PKD2 in more than 19 cancer types. Because this analysis shows association rather than direction, both PKD2-to-partner and partner-to-PKD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to hydrostatic pressure grouped by PKD2-low versus PKD2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD2→partner) and Y-score (partner→PKD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cellular response to hydrostatic pressure →	+0.180	+1.892	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.079	+1.567	<.001	<.001	3	18
CNS	Response to hydrostatic pressure →	+0.239	+1.248	.001	<.001	3	18
STOMACH	Cellular response to water stimulus →	+0.216	+1.813	<.001	<.001	3	17
STOMACH	Macroautophagy →	+0.060	+1.037	<.001	<.001	3	17
BONE	Autophagy →	+0.064	+1.077	.001	.005	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,185 associations by consensus.

Cellular response to hydrostatic pressure by PKD2 expression — STOMACH

Explore this box plot interactively →