PKD1

Across TCGA pan-cancer cohorts, PKD1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PKD1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PKD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PKD1 expression acts as an unfavorable survival marker.

LUAD and LSCC are the cancer types where PKD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.549	1.000	.018	13	view →
LSCC	DFS	Tertile	All	0.484	1.000	.030	5	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PKD1–LUAD (OS)

Open the LUAD breakdown →