Across TCGA patient cohorts, PJVK mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PJVK-associated genes across cancer lineages are eEF2, EGFR, and FoxM1. Each is linked with PJVK in more than 1 cancer types. Because this analysis shows association rather than direction, both PJVK-to-partner and partner-to-PJVK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PJVK→partner) and Y-score (partner→PJVK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.396	+1.700	.009	.044	3	1
UCEC	EGFR →	-0.184	-1.700	.006	.044	3	1
UCEC	FoxM1 →	+0.237	+1.700	.031	.044	3	1
UCEC	FOXO3a_pS318_S321 →	-0.125	-2.449	.018	.019	3	1
UCEC	GSK-3_pS9 →	-0.457	-2.000	.007	.030	3	1
UCEC	ACVRL1 →	-0.123	-3.302	.033	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

PJVK survival (RNA) · tumor vs normal (RNA) · all PJVK data types