PITPNM2

Across TCGA patient cohorts, PITPNM2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,794 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PITPNM2-associated genes across cancer lineages are FHL5, MYCT1, and SOCS2. Each is linked with PITPNM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PITPNM2-to-partner and partner-to-PITPNM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PITPNM2 versus FHL5 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNM2→partner) and Y-score (partner→PITPNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FHL5 →	+0.802	+0.542	.002	.004	3	3
UCEC	MYCT1 →	+0.783	+0.428	.004	.001	3	3
LSCC	SOCS2 →	+1.186	+0.293	<.001	<.001	3	3
UCEC	PTPRB →	+0.671	+0.610	<.001	.004	3	3
HNSC	GPAT3 →	+1.352	+1.707	<.001	.001	3	3
GBM	PDE2A →	+0.771	+0.254	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,794 associations by consensus.

PITPNM2 vs FHL5 — UCEC

Explore this scatter interactively →