PITPNM2

Across TCGA cell cohorts, PITPNM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,134 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PITPNM2-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Regulation of fibroblast proliferation, and Phosphatidylinositol phosphate biosynthetic process. Each is linked with PITPNM2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PITPNM2-to-partner and partner-to-PITPNM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by PITPNM2-low versus PITPNM2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNM2→partner) and Y-score (partner→PITPNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Phosphatidylinositol biosynthetic process →	+0.073	+1.279	<.001	.004	3	14
LARGE_INTESTINE	Regulation of fibroblast proliferation →	+0.073	+0.750	<.001	<.001	3	13
SKIN	Phosphatidylinositol phosphate biosynthetic process →	+0.056	+1.042	.001	.003	3	12
BONE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.136	+1.113	<.001	<.001	3	12
BONE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.136	+1.113	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Actin filament depolymerization →	+0.124	+0.549	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,134 associations by consensus.

Phosphatidylinositol biosynthetic process by PITPNM2 expression — STOMACH

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