PITPNM1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PITPNM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,537 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PITPNM1-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with PITPNM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both PITPNM1-to-partner and partner-to-PITPNM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by PITPNM1-low versus PITPNM1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNM1→partner) and Y-score (partner→PITPNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCilium or flagellum-dependent cell motility →-0.108-1.502<.001<.001314
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.108-1.502<.001<.001314
UPPER_AERODIGESTIVE_TRACTCilium movement involved in cell motility →-0.112-1.382<.001<.001314
BLOOD_MyelomaRegulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process →+1.269+2.177<.001<.001313
BLOOD_MyelomaPositive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process →+1.269+2.177<.001<.001313
UPPER_AERODIGESTIVE_TRACTMAPK cascade →+0.069+1.720<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,537 associations by consensus.

Cilium or flagellum-dependent cell motility by PITPNM1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Cilium or flagellum-dependent cell motility in PITPNM1-low vs PITPNM1-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration