PITPNC1

Across TCGA cell cohorts, PITPNC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,020 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PITPNC1-associated GO terms across cancer lineages are 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process, 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process, and Synaptic vesicle exocytosis. Each is linked with PITPNC1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PITPNC1-to-partner and partner-to-PITPNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process grouped by PITPNC1-low versus PITPNC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNC1→partner) and Y-score (partner→PITPNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process →	+0.163	+1.524	.002	<.001	3	17
SKIN	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process →	+0.104	+0.978	<.001	<.001	3	14
OVARY	Synaptic vesicle exocytosis →	+0.064	+1.097	<.001	<.001	3	7
SOFT_TISSUE	Phosphatidylinositol phosphate biosynthetic process →	+0.039	+1.218	.001	.005	2	7
LARGE_INTESTINE	Positive regulation of catecholamine secretion →	+0.261	+1.188	<.001	<.001	3	6
LUNG_NSCLC_LUSC	Negative regulation of cell growth involved in cardiac muscle cell development →	+0.143	+1.753	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,020 associations by consensus.

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process by PITPNC1 expression — BLOOD_Myeloma

Explore this box plot interactively →