PITPNA

Across TCGA cell cohorts, PITPNA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,401 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PITPNA-associated GO terms across cancer lineages are Mitotic centrosome separation, Positive regulation of pinocytosis, and Endosomal transport. Each is linked with PITPNA in more than 14 cancer types. Because this analysis shows association rather than direction, both PITPNA-to-partner and partner-to-PITPNA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by PITPNA-low versus PITPNA-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNA→partner) and Y-score (partner→PITPNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic centrosome separation →	+0.152	+0.763	.002	.004	3	15
BLOOD_Leukemia	Positive regulation of pinocytosis →	+0.138	+1.152	<.001	<.001	3	14
SKIN	Endosomal transport →	+0.058	+0.875	<.001	<.001	3	14
OVARY	Vesicle-mediated transport to the plasma membrane →	+0.050	+0.609	<.001	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.064	+0.693	<.001	<.001	3	13
SOFT_TISSUE	Cytosolic transport →	+0.078	+0.904	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,401 associations by consensus.

Mitotic centrosome separation by PITPNA expression — OESOPHAGUS

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