PIPOX

Across TCGA cell cohorts, PIPOX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,303 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PIPOX-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of nucleotide-excision repair. Each is linked with PIPOX in more than 11 cancer types. Because this analysis shows association rather than direction, both PIPOX-to-partner and partner-to-PIPOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by PIPOX-low versus PIPOX-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIPOX→partner) and Y-score (partner→PIPOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.722	<.001	<.001	3	11
STOMACH	Negative regulation of myoblast fusion →	+0.118	+0.997	.005	.001	2	11
STOMACH	Regulation of nucleotide-excision repair →	+0.143	+0.650	<.001	<.001	2	11
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.104	+0.720	.003	.007	3	10
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.100	+1.022	<.001	<.001	3	10
LUNG_SCLC	Regulation of myoblast fusion →	+0.078	+1.920	.009	<.001	1	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,303 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by PIPOX expression — LARGE_INTESTINE

Explore this box plot interactively →