PIP5KL1

Across TCGA patient cohorts, PIP5KL1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIP5KL1-associated genes across cancer lineages are SNRPD3, KDELR3, and RASL10A. Each is linked with PIP5KL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIP5KL1-to-partner and partner-to-PIP5KL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5KL1 versus SNRPD3 in GBM, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5KL1→partner) and Y-score (partner→PIP5KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.380	+0.500	.008	.009	3	1
GBM	KDELR3 →	-0.487	-0.486	<.001	.001	3	1
GBM	RASL10A →	+1.010	+0.552	.001	.001	3	1
GBM	NEFH →	+1.861	+0.616	<.001	<.001	3	1
GBM	CBX7 →	+0.593	+0.676	.001	.001	3	1
GBM	SYNGR1 →	+1.042	+0.746	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,126 associations by consensus.

PIP5KL1 vs SNRPD3 — GBM

Explore this scatter interactively →