PIP5KL1

Across TCGA patient cohorts, PIP5KL1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIP5KL1-associated genes across cancer lineages are lymphatic Endothelial cells and Mesangial cells. Each is linked with PIP5KL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIP5KL1-to-partner and partner-to-PIP5KL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by PIP5KL1-low versus PIP5KL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5KL1→partner) and Y-score (partner→PIP5KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.025	-3.129	.033	.019	3	1
UCEC	Mesangial cells →	-0.040	-2.311	.041	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

lymphatic Endothelial cells by PIP5KL1 expression — UCEC

Explore this box plot interactively →