PIP5KL1

Across TCGA cell cohorts, PIP5KL1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PIP5KL1-associated genes across cancer lineages are OOSP4B. Each is linked with PIP5KL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIP5KL1-to-partner and partner-to-PIP5KL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP4B grouped by PIP5KL1-low versus PIP5KL1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5KL1→partner) and Y-score (partner→PIP5KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OOSP4B →	+0.017	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OOSP4B by PIP5KL1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →