Across TCGA patient cohorts, PIP5K1C protein abundance is significantly associated with the RNA expression of many other genes, with 16,507 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIP5K1C-associated genes across cancer lineages are TGFB3, NAP1L3, and CXCL12. Each is linked with PIP5K1C in more than 7 cancer types. Because this analysis shows association rather than direction, both PIP5K1C-to-partner and partner-to-PIP5K1C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1C→partner) and Y-score (partner→PIP5K1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TGFB3 →	+0.958	+0.239	<.001	<.001	3	8
UCEC	NAP1L3 →	+1.191	+0.385	<.001	<.001	3	8
BRCA	CXCL12 →	+1.090	+0.241	<.001	<.001	3	7
LSCC	DCN →	+1.291	+0.338	<.001	<.001	3	7
BRCA	CNRIP1 →	+0.781	+0.227	<.001	<.001	3	7
GBM	ENOX1 →	+0.906	+0.413	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,507 associations by consensus.

Exploration

PIP5K1C survival (RNA) · tumor vs normal (RNA) · all PIP5K1C data types