Across TCGA patient cohorts, PIP5K1C protein abundance is significantly associated with the protein abundance of many other proteins, with 29,370 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIP5K1C-associated proteins across cancer lineages are NAA25, SGCD, and PHLDB1. Each is linked with PIP5K1C in more than 7 cancer types. Because this analysis shows association rather than direction, both PIP5K1C-to-partner and partner-to-PIP5K1C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1C→partner) and Y-score (partner→PIP5K1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NAA25 →	-0.241	-0.202	<.001	<.001	3	8
HNSC	SGCD →	+0.822	+0.292	<.001	<.001	3	8
UCEC	PHLDB1 →	+0.465	+0.320	<.001	<.001	3	8
COAD	GUCY1A1 →	+0.437	+0.390	<.001	<.001	3	8
BRCA	HSPA12B →	+0.496	+0.174	<.001	<.001	3	8
GBM	IARS1 →	-0.221	-0.322	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,370 associations by consensus.

Exploration

PIP5K1C survival (RNA) · tumor vs normal (RNA) · all PIP5K1C data types