Across TCGA patient cohorts, PIP5K1C mutation is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIP5K1C-associated genes across cancer lineages are TBC1D3P1-DHX40P1, RNA5SP53, and FAM138D. Each is linked with PIP5K1C in more than 2 cancer types. Because this analysis shows association rather than direction, both PIP5K1C-to-partner and partner-to-PIP5K1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1C→partner) and Y-score (partner→PIP5K1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TBC1D3P1-DHX40P1 →	+0.009	+2.965	<.001	.008	3	3
HNSC	RNA5SP53 →	+0.246	+5.015	.003	.009	3	2
CESC	FAM138D →	+0.020	+4.342	<.001	.007	3	2
CESC	MIR4510 →	+0.195	+4.342	<.001	.007	3	2
CESC	TMEM207 →	+0.221	+3.684	.001	.005	3	2
UCEC	NOL12 →	+0.259	+2.447	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

Exploration

PIP5K1C survival (RNA) · tumor vs normal (RNA) · all PIP5K1C data types