PIP5K1C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PIP5K1C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,751 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PIP5K1C-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Negative regulation of transcription initiation by RNA polymerase II, and Negative regulation of DNA-templated transcription initiation. Each is linked with PIP5K1C in more than 16 cancer types. Because this analysis shows association rather than direction, both PIP5K1C-to-partner and partner-to-PIP5K1C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1C→partner) and Y-score (partner→PIP5K1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHPositive regulation of anaphase-promoting complex-dependent catabolic process →+0.186+0.833<.001<.001317
LARGE_INTESTINENegative regulation of transcription initiation by RNA polymerase II →+0.118+0.901<.001<.001317
LARGE_INTESTINENegative regulation of DNA-templated transcription initiation →+0.118+0.901<.001<.001317
STOMACHEndosomal transport →+0.067+0.813<.001<.001317
UPPER_AERODIGESTIVE_TRACTRegulation of androgen receptor signaling pathway →+0.082+0.898.001<.001316
OESOPHAGUSCytosolic transport →+0.075+0.968.004.008316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,751 associations by consensus.

Exploration