PIP5K1B

Across TCGA pan-cancer cohorts, PIP5K1B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PIP5K1B data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PIP5K1B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PIP5K1B expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LUAD and HNSC are the cancer types where PIP5K1B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.213	0.676	.012	6	view →
HNSC	OS	Median	IV	0.861	0.334	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PIP5K1B–LUAD (DFS)

Open the LUAD breakdown →