PIP5K1B

Across TCGA patient cohorts, PIP5K1B RNA expression is significantly associated with the protein abundance of many other proteins, with 17,029 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PIP5K1B-associated proteins across cancer lineages are SEPTIN4, ADD3, and ANK2. Each is linked with PIP5K1B in more than 5 cancer types. Because this analysis shows association rather than direction, both PIP5K1B-to-partner and partner-to-PIP5K1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5K1B versus SEPTIN4 in GBM, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1B→partner) and Y-score (partner→PIP5K1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN4 →	+0.713	+0.875	<.001	<.001	3	6
BRCA	ADD3 →	+0.592	+1.061	<.001	<.001	3	6
HNSC	ANK2 →	+0.636	+0.980	<.001	<.001	3	6
CCRCC	TNXB →	+0.643	+0.370	<.001	.009	3	6
GBM	P4HA1 →	-0.629	-0.692	<.001	.004	3	6
HNSC	TJP3 →	+0.340	+0.460	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,029 associations by consensus.

PIP5K1B vs SEPTIN4 — GBM

Explore this scatter interactively →