PIP5K1B

Across TCGA patient cohorts, PIP5K1B protein abundance is significantly associated with the RNA expression of many other genes, with 9,595 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIP5K1B-associated genes across cancer lineages are ILVBL, TXNDC17, and C7orf50. Each is linked with PIP5K1B in more than 1 cancer types. Because this analysis shows association rather than direction, both PIP5K1B-to-partner and partner-to-PIP5K1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5K1B versus ILVBL in LSCC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1B→partner) and Y-score (partner→PIP5K1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ILVBL →	-0.767	-0.522	.003	.003	3	2
LUAD	TXNDC17 →	-1.150	-0.742	<.001	<.001	3	2
LUAD	C7orf50 →	-0.864	-0.600	<.001	<.001	3	2
LUAD	GPX4 →	-0.682	-0.502	<.001	.002	3	2
LUAD	RNF135 →	-0.748	-0.467	<.001	.005	3	2
LSCC	SMIM29 →	-0.544	-0.609	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,595 associations by consensus.

PIP5K1B vs ILVBL — LSCC

Explore this scatter interactively →