PIP5K1B

Across TCGA patient cohorts, PIP5K1B mutation is significantly associated with the RNA expression of many other genes, with 3,924 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIP5K1B-associated genes across cancer lineages are RNU6-454P, LINC02650, and SLC25A33. Each is linked with PIP5K1B in more than 2 cancer types. Because this analysis shows association rather than direction, both PIP5K1B-to-partner and partner-to-PIP5K1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-454P grouped by PIP5K1B-low versus PIP5K1B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1B→partner) and Y-score (partner→PIP5K1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-454P →	+0.473	+8.471	<.001	.005	3	3
BRCA	LINC02650 →	+0.178	+8.055	<.001	.007	3	3
UCEC	SLC25A33 →	+0.532	+2.593	<.001	<.001	3	3
SKCM	RNU6-1131P →	+0.063	+4.647	<.001	.001	3	3
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	3
CESC	KRTAP10-11 →	+0.028	+4.424	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,924 associations by consensus.

RNU6-454P by PIP5K1B expression — BRCA

Explore this box plot interactively →