PIP5K1B

Across TCGA cell cohorts, PIP5K1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PIP5K1B-associated GO terms across cancer lineages are Fibrinolysis, Regulation of atrial cardiac muscle cell membrane repolarization, and 2-oxoglutarate metabolic process. Each is linked with PIP5K1B in more than 8 cancer types. Because this analysis shows association rather than direction, both PIP5K1B-to-partner and partner-to-PIP5K1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibrinolysis grouped by PIP5K1B-low versus PIP5K1B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1B→partner) and Y-score (partner→PIP5K1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Fibrinolysis →	-1.286	-1.678	<.001	<.001	3	8
BREAST	Regulation of atrial cardiac muscle cell membrane repolarization →	-0.266	-0.692	<.001	<.001	3	8
LARGE_INTESTINE	2-oxoglutarate metabolic process →	+0.109	+1.960	<.001	<.001	3	8
STOMACH	Peptidyl-lysine oxidation →	-1.362	-2.555	<.001	<.001	3	8
BLOOD_Lymphoma	Detoxification of copper ion →	-0.186	-1.102	.001	.004	3	8
BLOOD_Lymphoma	Stress response to copper ion →	-0.186	-1.102	.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

Fibrinolysis by PIP5K1B expression — LARGE_INTESTINE

Explore this box plot interactively →