PIP4P2

Across TCGA pan-cancer cohorts, PIP4P2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PIP4P2 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PIP4P2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PIP4P2 expression acts as an unfavorable survival marker.

CCRCC, UCEC, and PDAC are the cancer types where PIP4P2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.704	1.000	.001	28	view →
UCEC	OS	Median	II,III,IV	0.595	1.000	.005	26	view →
PDAC	OS	Median	II,III,IV	0.767	0.923	.006	18	view →
LUAD	OS	Quartile	All	0.971	1.000	.023	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PIP4P2–CCRCC (OS)

Open the CCRCC breakdown →