PIP4P2

Across TCGA patient cohorts, PIP4P2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,857 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIP4P2-associated genes across cancer lineages are FPR1, CD22, and NCF1. Each is linked with PIP4P2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PIP4P2-to-partner and partner-to-PIP4P2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP4P2 versus FPR1 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4P2→partner) and Y-score (partner→PIP4P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FPR1 →	+0.969	+0.244	<.001	.007	3	5
COAD	CD22 →	+1.277	+0.648	<.001	.001	3	3
COAD	NCF1 →	+0.798	+0.715	.004	<.001	3	3
UCEC	EIF2B1 →	-0.611	-0.349	.009	<.001	3	3
LSCC	CPSF3 →	-0.417	-0.228	<.001	<.001	3	3
LSCC	BPHL →	-0.517	-0.282	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,857 associations by consensus.

PIP4P2 vs FPR1 — GBM

Explore this scatter interactively →