PIP4P2

Across TCGA cell cohorts, PIP4P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,739 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIP4P2-associated GO terms across cancer lineages are Phosphatidylinositol dephosphorylation, Protein import into peroxisome membrane, and Vesicle cargo loading. Each is linked with PIP4P2 in more than 14 cancer types. Because this analysis shows association rather than direction, both PIP4P2-to-partner and partner-to-PIP4P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol dephosphorylation grouped by PIP4P2-low versus PIP4P2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4P2→partner) and Y-score (partner→PIP4P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Phosphatidylinositol dephosphorylation →	+0.080	+1.259	.007	.003	2	15
UPPER_AERODIGESTIVE_TRACT	Protein import into peroxisome membrane →	+0.137	+1.269	.002	.001	3	10
BLOOD_Lymphoma	Vesicle cargo loading →	+0.066	+1.176	<.001	<.001	3	10
BLOOD_Lymphoma	Synaptic vesicle lumen acidification →	+0.128	+1.354	<.001	<.001	3	10
LIVER	Golgi lumen acidification →	+0.096	+0.830	.001	.006	3	9
STOMACH	Negative regulation of negative chemotaxis →	+1.313	+2.340	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,739 associations by consensus.

Phosphatidylinositol dephosphorylation by PIP4P2 expression — LIVER

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