PIP4P1

Across TCGA cell cohorts, PIP4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,160 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PIP4P1-associated GO terms across cancer lineages are Establishment of vesicle localization, Positive regulation of autophagy, and Cellular response to nutrient levels. Each is linked with PIP4P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PIP4P1-to-partner and partner-to-PIP4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of vesicle localization grouped by PIP4P1-low versus PIP4P1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4P1→partner) and Y-score (partner→PIP4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of vesicle localization →	+0.053	+0.880	<.001	<.001	3	13
PANCREAS	Positive regulation of autophagy →	+0.054	+0.788	.002	<.001	3	12
LUNG_SCLC	Cellular response to nutrient levels →	+0.056	+0.808	<.001	<.001	3	12
LUNG_SCLC	DNA ADP-ribosylation →	+0.130	+0.734	.001	<.001	3	11
KIDNEY	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.061	+0.984	.001	<.001	3	11
URINARY_TRACT	Response to starvation →	+0.053	+0.877	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,160 associations by consensus.

Establishment of vesicle localization by PIP4P1 expression — BREAST

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