PIP4K2A

Across TCGA patient cohorts, PIP4K2A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,887 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIP4K2A-associated proteins across cancer lineages are TNFAIP8L2, DOCK2, and EVL. Each is linked with PIP4K2A in more than 7 cancer types. Because this analysis shows association rather than direction, both PIP4K2A-to-partner and partner-to-PIP4K2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP4K2A versus TNFAIP8L2 in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2A→partner) and Y-score (partner→PIP4K2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TNFAIP8L2 →	+0.593	+0.641	<.001	<.001	3	7
GBM	DOCK2 →	+0.754	+1.062	<.001	<.001	3	7
OV	EVL →	+0.549	+0.857	.001	<.001	3	7
GBM	HCLS1 →	+0.800	+0.811	<.001	<.001	3	7
OV	WAS →	+0.444	+0.712	<.001	<.001	3	7
HNSC	WIPF1 →	+0.410	+0.471	<.001	.006	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,887 associations by consensus.

PIP4K2A vs TNFAIP8L2 — COAD

Explore this scatter interactively →