PIP4K2A

Across TCGA patient cohorts, PIP4K2A protein abundance is significantly associated with the RNA expression of many other genes, with 17,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIP4K2A-associated genes across cancer lineages are LY86, GMFG, and DPEP2. Each is linked with PIP4K2A in more than 9 cancer types. Because this analysis shows association rather than direction, both PIP4K2A-to-partner and partner-to-PIP4K2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP4K2A versus LY86 in OV, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2A→partner) and Y-score (partner→PIP4K2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LY86 →	+1.244	+0.647	<.001	<.001	3	10
HNSC	GMFG →	+1.242	+0.471	<.001	<.001	3	10
HNSC	DPEP2 →	+0.703	+0.400	<.001	<.001	3	10
LSCC	CCDC69 →	+1.017	+0.446	<.001	<.001	3	10
LSCC	RCSD1 →	+0.943	+0.435	<.001	<.001	3	10
HNSC	CYTH4 →	+0.986	+0.326	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,200 associations by consensus.

PIP4K2A vs LY86 — OV

Explore this scatter interactively →